You’re feeling ill. You visit the doctor, pick up a script and head to the pharmacy to collect your meds. The person in front of you in the queue just came from the doctor too. And they have the same script. Once you’ve both taken your medication, you’ll feel an equal improvement, right? Wrong. Due to slight genetic variations in your DNA, you might metabolise and process the medication you’re taking differently to the person in front you. The ingredients in the pills you’re taking might stay in your body for three hours longer. They may have much more serious side effects. Or they may have no effect whatsoever. You’d probably never know – except you’d never feel quite right, and could have chronic side effects while taking the medication. But you should learn to live with the side effects, right? Wrong again, fortunately. Most patients put up with frustrating side effects, simply because they think they have to. But with a little more knowledge of their DNA, they could be working with their doctor to find a tailored solution with far higher likelihood of working. And to a large extent, leaving ineffective meds and unwanted side effects behind,. Distinct DNA difference Molecular biologist and founder of DNAlysis Biotechnology, Dr Daniel Meyersfeld, believes most South Africans simply aren’t aware of the various ways their unique DNA affects metabolism of medication. “Many patients don’t respond to the first drug they’re prescribed in the course of treatment. A trial and error approach is frustrating and expensive, so why not use genetic information to streamline the process?” says Meyersfeld. “By conducting a simple genetic test, patients and doctors can now work towards enhancing the safety and efficacy of their treatment and avoiding unpleasant side effects.” Warfarin – the way forward Meyersfeld speaks specifically of Warfarin as a stellar example of prescription that should be tailored to the individual. Warfarin is the anticoagulant of choice . . .
Centurion, Gauteng, 28 February 2017 – Representatives from Nexia SAB&T and Indyebo, announced today that the two companies will be merging effective 1 March 2017. The business will continue to trade under the Nexia SAB&T brand, to emphasise its ties to the 10th largest international network in the sector, Nexia International. Nexia SAB&T is a top ten audit, accounting and consulting professional services provider, with a history that dates back to the birth of democracy in South Africa, having been founded in 1994. Nexia SAB&T has always strived to reflect the demographics of the country in its ownership structure, while providing a service to its clients that is inspired by a vision to be “Closer to you!” Indyebo is a progressive Black female owned firm that offers assurance, advisory and consulting services and has an outstanding reputation for quality, excellence and integrity. The merger has come about as a natural development out of several projects undertaken by Nexia SAB&T and Indyebo jointly. Nexia SAB&T has long identified Indyebo as a candidate for its enterprise development initiatives and as such shared a long and mutually beneficial shared relationship with Indyebo over the years. With the other Black owned assurance provider firms in the market having experienced growth in the past years, this merger will see Nexia SAB&T solidifying its position among South Africa’s top ten audit firms as well as, as one of the premier Black empowerment firms. Nexia SAB&T is truly a multi-disciplinary professional service provider, with a wide range of services and accreditations in the audit, accounting and consulting fields. These include JSE accreditation for the conduct of audits of listed entities, a national footprint with offices in each of South Africa’s nine provinces and experience in the private and public sector at all levels. Bashier Adam, CEO and founder of Nexia SAB&T explained the new direction of the . . .
The annual Sanlam Top Destination Awards, in its third year running, plans to expand this year with additional entries, more guests at the awards ceremony, extravagant décor and further prolific sponsorship opportunities with the theme of Authentically African #MyHeartBeatsAfrica. The awards have been designed by Discount Traveler for one purpose and that’s to uplift the hospitality industry in South Africa by acknowledging top accommodation establishments as key industry players. Managing Director of Discount Traveler, Jonathan Pepler states that the Sanlam Top Destination Awards far exceeds our expectations, especially due to the great response we’ve received each year. “We are building a brand that will continue to show recognition to one of our country’s most influential industries and one that has a positive impact. The hospitality and tourism industry in its entirety is a driving force in our economy and to simply play a small role in this, is significant to the bigger picture.” Pepler continues, “We strive to uplift that local family business that has put blood, sweat and tears into their establishment, to show people the utmost dedication that goes into running a guest house or B&B and then on the other hand we want to show recognition to the four and five-star hotels that are doing everything right in terms of service offering and deserve an applause.” Entries are open to all accommodation establishments in South Africa and there are nine categories available to enter. Entries have been open from the 1st of February 2017 but voting will commence from the 1st of March 2017. Voting is open to the public and establishments are encouraged to get their guests to vote for them. Votes are tallied and the top establishments are then judged according to an internal set of criteria. Nominees are named and winners will be announced at the awards ceremony on Thursday, 14 September 2017 which will be held at the Cape Town City Hall. Title sponsor of . . .
Unbelievably - it is almost THAT time of the year again! Every year we are building up the excitement to ... National Tekkie Tax Day! It has been the talk of the town on the SA calendar for the past four years. This year, Tekkie Tax day will be celebrated on Friday, 26 May 2017. The campaign gives you the opportunity to “bead-up your step” and show everyone else where your heart lies. It is as easy as 1 . . .2 . . .3! 1. Choose your sticker for a cause close to your heart, 2. Shoooosh up your Tekkies with their funky shoelaces, and 3. You are ready for National Tekkie Tax Day! Tekkie Tax is the funkiest, trendiest, most innovative, unique and successful national fundraising campaign for welfare organisations in SA. It started in 2013 when a few of South Africa’s biggest and most accountable welfare organisations joined forces. Since its inception, they have already raised a whopping R22 million for participating NGO’s. There are 12 National Beneficiaries and they represent more than a 1 000 local non-profit organisations. They are: Epilepsy SA, Child Welfare SA, SOS Children's Villages, CHOC, Special Olympics SA, CANSA, Imisebeyelanga Services, Meals on Wheels, VVA, NG Welfare, SAVF and Endurocad. The Project has been growing each year and Tekkie Tax thought it necessary to bring another family member on board! And this is how Happy became part of the Tekkie Tax family. . . Happy is the new Tekkie Tax Mascot with a BIG heart! He is a boisterous little character and always ready to have some fun. With such a joyous little character on board, everybody HAS TO participate in the 2017 campaign. The stickers (for a donation of R10 each) and the Tekkie Tax shoelaces (R35 per pair) are available at all ToysRUs/BabiesRUs and Clicks stores nationwide. There are also more than 280 participating non-profit organisations selling these items and together they aim to convince every South African to be part of the fun. Orders can also be placed online via the . . .
It’s 6:45. You’re hosting dinner at 7. You earnestly asked your partner to be home at 6, and buy cheese for the salad on their way home. You’ve tried to call them – their phone is off. You’re stuck preparing for your guests all alone and don’t know how someone could be so inconsiderate to leave you in this position. Sound familiar? The core symptoms of Attention Deficit Hyperactivity Disorder (ADHD) – inattentiveness, hyperactivity and impulsivity – can often be mistaken for a disregard of a partner’s emotions, and lead to unnecessary conflict. Psychiatrist Dr Rykie Liebenberg believes the symptoms of ADHD have a ripple effect on all areas of a relationship. Learning to listen “Partners of individuals with ADHD constantly feel as if they’re not being heard because their requests aren’t fulfilled – whether it’s completing household tasks or meeting their broader emotional needs. They understand this to mean their partner doesn’t care enough and isn’t invested in the relationship,” explains Liebenberg. “In reality, it’s simply the inattentiveness that often goes hand-in-hand with ADHD.” Temper traps A quick temper and high levels of aggression can also make individuals with ADHD appear as if they’re disinvested in the relationship. Liebenberg says untreated ADHD can lead to emotional outbursts and irritability – often in traffic or busy areas like shopping malls – which can lead to arguments. “ADHD-related impulsivity can also pose major challenges for a someone living with a partner with ADHD. The partner is mistakenly seen as irresponsible and uncaring because they spend money that should be reserved for household expenses, walk out of jobs without consulting their family or engage in gambling or extra-marital relationships.” Affecting intimacy The combination of these negative symptoms of ADHD go to the core of a relationship, says Liebenberg, and ultimately affect its basic functioning – right down to intimacy. “If you’re constantly . . .
Research shows only a third of patients are familiar with personalised medicine – and only 11% have broached the topics with their doctor. Considering around 38% of patients with depression, 50% of arthritis patients, 40% of asthma patients and 43% of diabetic patients won’t react to the first treatment they’re prescribed, these statistics are concerning. Experts in the field believe the knowledge gap around personalised medicine – and reluctance of some healthcare professionals to embrace it – is halting the advancement of healthcare systems. What is personalised medicine? Personalised medicine – also known as precision medicine – is an emerging practice of medicine that uses an individual’s genetic profile to guide prevention, diagnosis and treatment of disease. One of the foundations of personalised medicine is pharmacogenomics: using genetic biomarkers that influence drug response to guide drug therapy decisions for individual patients. Historical approach The lack of knowledge around personalised medicine is largely as a result of the ‘one-dose-fits-all’ approach used to treat diseases throughout history. Medicine has traditionally revolved around ‘standards of care’ – what’s believed to be the most effective treatment for the general population. Often, this is considered to be the most reasonable treatment, but has little to do with the patient specifically. The findings from the Human Genome Project, released in 2003, gave momentum to the personalised medicine movement. The Project revealed the DNA of any two individuals is 99.9% identical. Variations in the 0.1% of a person’s DNA, it was discovered, influence the genes that code for drug-metabolising enzymes or drug transporters. This means a significant portion of the population will each metabolise medications in a unique way to another patient. Small change, big consequences A small genetic variation in genes that control drug-metabolising enzymes also contribute to adverse events . . .
The Water Efficient Maize for Africa (WEMA) Project – an international private-public partnership – show cased new insect-protected maize hybrids earlier this month in Gatyana (Willowvale) in the Eastern Cape. The programme aims to enhance food security and improve rural livelihoods among smallholder farmers in sub-Saharan Africa through development and deployment of drought-tolerant and insect-protected maize hybrids. The WEMA project started in 2008 and is led by the African Agricultural Technology Foundation (AATF) based in Kenya, and is funded by the Bill and Melinda Gates Foundation, the Howard G Buffet Foundation and USAID. Other partners include: Monsanto Company, International Maize and Wheat Improvement Center (CIMMYT) and National Agricultural Research Systems of Kenya, Mozambique, South Africa (ARC), Tanzania and Uganda. Earlier this week WEMA partners visited smallholder farmers in the Eastern Cape and presented an Information day which was hosted and funded by the Agricultural Research Council (ARC), in collaboration with the Eastern Cape Department of Rural Development and Agrarian Reform (DRDAR). The ARC and DRDAR planted maize demonstration plots comprised of five TELATM brand Bt (MON89034) maize hybrids that have been submitted by ARC to DAFF for registration. Some 2kg promotional packs of the Bt hybrids had been distributed to smallholder farmers for on-farm trials. “The Eastern Cape is one of the hot spot provinces for stalk borer, which is also associated with high levels of ear rots and the associated mycotoxins which can cause oesophageal cancer. It is therefore one of the prime target provinces for deployment of the royalty-free WEMA Bt technology,” said Mark Edge, Director of WEMA Partnerships – Monsanto, one of the WMA partner companies. The WEMA partners have developed the largest conventional breeding and regulated testing network for maize in Africa and the partnership helps build technical capacity in Africa to use . . .
Launching this month is SEESA ProFile, a comprehensive software system designed to guide business owners in navigating labour legislation of South Africa. From February 2017 the software system is available to South African business owners across the country. ProFile allows business owners to manage their labour force in a way not seen before. The system integrates with any business, allowing business owners to take matters such as issuing warnings and notices for labour-related offences, grievances and hearings in their own hands. All documents are prepopulated with employees’ details and stored electronically for record keeping, lessening the administrative burden on personnel. ProFile has a built-in feature for on-screen guidance to assist users in following the correct procedures for all labour issues. This system removes any uncertainty from legal procedures. The purpose of ProFile is to move away from manual administration and filing, ensuring that everyday Human Resources and Industrial Relations functions are completed correctly and electronically. ProFile captures and stores employee details and disciplinary records with prepopulated document templates for all misconduct procedures. ProFile was built intelligently and intuitively – if you are issuing a notice of hearing for a specific employee without having issued a relevant warning first, the software will advise the user of the correct action to be taken instead, guiding you to complete compliance. “In our experience, employers lose CCMA cases largely due to incorrect and inconsistent procedures, where documents are issued incorrectly or going missing – ProFile addresses these issues.” - SEESA SEESA provides professional legal support for businesses in South Africa and since its beginning in 1998, their largest service to South African business owners was assistance in implementing labour legislation. Over the years, SEESA identified a pattern of recurring problems most small business . . .
Auto Agent, the maker of brilliant car dealer websites in South Africa has partnered with a leading car sales website. This partnership enables car dealers to push their vehicle stock to multiple platforms from their own dealer site. Car dealer website company Auto Agent celebrates it's sixth year of serving South African car dealerships with high quality websites. From it's outset, the goal was to optimise dealer sites for mobile audiences by providing mobile friendly navigation as standard across it's customer interfaces. Used car dealers responded positively to the Auto Agent sales platform with it's mobile friendly navigation and easy to use administration, catering for the website stock management, 3rd party advertising, promotions and staff management. Leads management that features SMS notification, email and database storage that can be output as XLS spreadsheets for later analysis. Most recently, Auto Agent has partnered with cars.co.za (and previously with olx.co.za) to facilitate a streamlined inventory upload across multiple selling platforms. This means that dealers now have 3 powerful sales platforms from which they can generate sales leads: pickacar.co.za, usedcarsforsale.co.za and the recent addition of cars.co.za. This has been one of the strengths behind the Auto Agent platform as it frees the dealer from having to manually load his vehicle stock across multiple car selling sites. Auto Agent is particularly excited to offer Cars.co.za on it's platform as they have become a major player in the online used car sales space. Back in 2011, founder Pierre Theron saw that the used car dealerships were not well served and that many home grown solutions and DIY dealer sites simply generated more admin for car dealerships. Apart from loading to the 3rd party automotive sales websites, car dealers were burdened by having to load to their own websites too, with little benefit. The Auto Agent catchphrase "load once" was coined and dealers were now . . .
07 February 2017, Johannesburg, South Africa – Thembisa Mdoda is the loved face of the popular reality series, Our Perfect Wedding, however, there is more to her than meets the eye. Thembisa Mdoda is a creative soul with three degrees under her belt (Graphic Design, Hon. Dramatic Arts, Media Studies and Journalism) adding credibility to her skills and talents as an entertainer and journalist. To showcase all her talents, Thembisa has joined well-known talent management agency, Owen S. Management. Owen S. Management specializes in representing, managing and promoting high-profiled media personalities, professional actors and skilled voice-over artists. With their vast experience in the entertainment industry, Owen S. Management is the chosen agency to take Thembisa Mdoda’s career to new levels. Thembisa Mdoda has decided to venture back into acting and where better to start than with joining an agency that not only can represent Thembisa as an actor but to also further strengthen her presence as a media personality. “I am very excited for this new journey that I am about to embark on and I feel confident because Owen S. Management understands what I want and they have the experience and the personal touch to get me there. I cannot wait for my fans to see what we work on throughout the year,” says Thembisa Mdoda. 2017 is deemed to be the year to do and be better and Thembisa Mdoda is showing that there is no time to waste by taking charge of her career. “We have a solid pool of talent we work with and we are thrilled to have Thembisa join us. We are passionate about what we do and we are passionate about our artists. I’ve had my eye on Thembisa for a while now. I respect and admire how she’s had staying power as a media personality and what excites me more is that I think she’s just getting started! We’re excited to take her career to greater heights,” concludes Owen Swanson, Managing Director and Founder of Owen S. Management. CLICK HERE to submit . . .